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Journal: Biomedical Reports
Article Title: Biochanin‑A as SIRT‑1 modulator in preventing statin‑associated diabetogenesis: An in vitro study
doi: 10.3892/br.2025.1969
Figure Lengend Snippet: BA promotes the proliferation of L6 and MIN-6 cells. (A) L6 Cells were treated with varying concentrations of Atorvastatin to determine the IC 50 and the cell proliferation with the combination of Atorvastatin and BA by SRB assay. The value is represented as the mean ± SEM (n=3). (B) MIN-6 Cells were treated with BA against Atorvastatin-induced cytotoxicity. IC 50 of BA and Atorvastatin was analyzed. The highest cell proliferation was observed for the combination of Atorvastatin with 50 and 100 µM BA. The value is presented as the mean ± SEM (n=3). BA, Biochanin-A; SRB, sulforhodamine B.
Article Snippet: The mouse pancreatic beta cell line (MIN-6) and
Techniques: Sulforhodamine B Assay